The LinuxSampler project was founded in 2002 with the goal to produce a free, (cross-platform), streaming capable, open source, pure software audio sampler with high stability, efficiency and very low latency, while providing professional grade features, comparable to both hardware and commercial Windows / Mac software samplers and to introduce new features not yet available by any other sampler in the world.

linuxsampler.org

Visual Front Ends ~ GUI:

QSampler

JSampler